Human Prothrombin Complex Concentrate
Octaplex® is a human four factor prothrombin complex concentrate (4F-PCC) containing Factors II, VII, IX and X, as well as inhibitor protein C and its cofactor protein S. It is an effective and convenient treatment to restore the levels of prothrombin complex coagulation factors in cases of congenital deficiency (of factor II or X, when an individual factor concentrate is not available) or acquired deficiency, such as deficiency provoked by the use of vitamin K antagonists (VKA) for anticoagulation therapy.
Octaplex® undergoes two specific pathogen inactivation/removal steps:
Octaplex® is presented in vials containing 500 IU and 1000 IU of human prothrombin complex. The total protein content per vial is 260–820 mg (500 IU vial)/ 520–1640 mg (1000 IU vial). The specific activity of the product is ≥ 0.6 IU/mg proteins, expressed as factor IX activity.
Do not store above 25°C, do not freeze. Store in the original package in order to protect from light. The shelf life is three years.
1. Octaplex® - Summary of Product Characteristics (EU)
You are now on Octapharma’s global website. Please select your country from the menu at the top of this page to access more detailed country-specific information or to contact your local Octapharma team.